USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

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Searching in 'USC-OGP 2-DE database' for entry matching: P63104 USC-OGP 2-DE database:  P63104 P63104 General information about the entry View entry in simple text format Entry name 1433Z_HUMAN Primary accession number P63104 Secondary accession number(s) P29312 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=14-3-3 protein zeta/delta; AltName: Full=Protein kinase C inhibitor protein 1; Short=KCIP-1;. Gene name Name=YWHAZ Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein PLATELET_4-5 {PLATELET 4-5} Homo sapiens (Human)   map experimental info   PLATELET_4-5 MAP LOCATIONS: SPOT OGP-0164: pI=4.90; Mw=28692 SPOT OGP-0171: pI=4.69; Mw=27997 SPOT OGP-0178: pI=4.66; Mw=26878 UVEAL_MELANOMA_3-10 {UVEAL MELANOMA 3-10} Homo sapiens (Human)   map experimental info   UVEAL_MELANOMA_3-10 MAP LOCATIONS: SPOT OGP-1271: pI=4.06; Mw=27991 Cross-references UniProtKB/Swiss-Prot P63104; 1433Z_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name 1433Z_HUMAN Primary accession number P63104 Secondary accession number(s) A8K1N0 B7Z465 P29213 P29312 Q32P43 Q5XJ08 Q6GPI2 Q6IN74 Q6NUR9 Q6P3U9 Q86V33 Sequence was last modified on  September 13, 2004 (version 1) Annotations were last modified on  March 15, 2017 (version 159) Name and origin of the protein Description RecName: Full=14-3-3 protein zeta/delta; AltName: Full=Protein kinase C inhibitor protein 1; Short=KCIP-1; Gene name Name=YWHAZ Encoded on Name=YWHAZ Keywords 3D-structure; Acetylation; Alternative splicing; Complete proteome; Cytoplasm; Direct protein sequencing; Phosphoprotein; Reference proteome. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL M86400; AAA36446.1; -; mRNA EMBL U28964; AAC52052.1; -; mRNA EMBL AK289945; BAF82634.1; -; mRNA EMBL AK296902; BAH12451.1; -; mRNA EMBL CH471060; EAW91823.1; -; Genomic_DNA EMBL BC003623; AAH03623.3; -; mRNA EMBL BC051814; AAH51814.1; ALT_INIT; mRNA EMBL BC063824; AAH63824.2; -; mRNA EMBL BC068456; AAH68456.2; -; mRNA EMBL BC072426; AAH72426.2; -; mRNA EMBL BC073141; AAH73141.1; ALT_INIT; mRNA EMBL BC083508; AAH83508.2; -; mRNA EMBL BC099904; AAH99904.1; -; mRNA EMBL BC101483; AAI01484.1; -; mRNA EMBL BC108281; AAI08282.1; -; mRNA EMBL BC111951; AAI11952.1; -; mRNA CCDS CCDS6290.1; -. [P63104-1]; . PIR A38246; PSHUAM; . RefSeq NP_001129171.1; NM_001135699.1. [P63104-1]; . RefSeq NP_001129172.1; NM_001135700.1. [P63104-1]; . RefSeq NP_001129173.1; NM_001135701.1. [P63104-1]; . RefSeq NP_001129174.1; NM_001135702.1. [P63104-1]; . RefSeq NP_003397.1; NM_003406.3. [P63104-1]; . RefSeq NP_663723.1; NM_145690.2. [P63104-1]; . RefSeq XP_005251118.1; XM_005251061.3. [P63104-1]; . RefSeq XP_005251120.1; XM_005251063.3. [P63104-1]; . RefSeq XP_016869299.1; XM_017013810.1. [P63104-1]; . RefSeq XP_016869300.1; XM_017013811.1. [P63104-1]; . UniGene Hs.492407; -; . PDB 1IB1; X-ray; 2.70 A; A/B/C/D=1-245 PDB 1QJA; X-ray; 2.00 A; A/B=1-245 PDB 1QJB; X-ray; 2.00 A; A/B=1-245 PDB 2C1J; X-ray; 2.60 A; A/B=1-245 PDB 2C1N; X-ray; 2.00 A; A/B=1-245 PDB 2O02; X-ray; 1.50 A; A/B=1-230 PDB 2WH0; X-ray; 2.25 A; A/B/C/D=1-245 PDB 3CU8; X-ray; 2.40 A; A/B=1-245 PDB 3NKX; X-ray; 2.40 A; A/B=1-245 PDB 3RDH; X-ray; 2.39 A; A/B/C/D=1-245 PDB 4BG6; X-ray; 2.30 A; A/B=1-245 PDB 4FJ3; X-ray; 1.95 A; A/B=1-230 PDB 4HKC; X-ray; 2.20 A; A=1-245 PDB 4IHL; X-ray; 2.20 A; A/B=1-230 PDB 4N7G; X-ray; 2.25 A; A=1-230 PDB 4N7Y; X-ray; 2.16 A; A/B=1-230 PDB 4N84; X-ray; 2.50 A; A/B=1-230 PDB 4WRQ; X-ray; 2.41 A; A/B=1-245 PDB 4ZDR; X-ray; 2.90 A; A/B=1-230 PDB 5D2D; X-ray; 2.10 A; A/B=1-230 PDB 5D3F; X-ray; 2.74 A; A/B=1-230 PDB 5EWZ; X-ray; 2.34 A; A/B=1-230 PDB 5EXA; X-ray; 1.95 A; A/B=1-230 PDB 5J31; X-ray; 2.40 A; A/B=1-230 PDBsum 1IB1; -; . PDBsum 1QJA; -; . PDBsum 1QJB; -; . PDBsum 2C1J; -; . PDBsum 2C1N; -; . PDBsum 2O02; -; . PDBsum 2WH0; -; . PDBsum 3CU8; -; . PDBsum 3NKX; -; . PDBsum 3RDH; -; . PDBsum 4BG6; -; . PDBsum 4FJ3; -; . PDBsum 4HKC; -; . PDBsum 4IHL; -; . PDBsum 4N7G; -; . PDBsum 4N7Y; -; . PDBsum 4N84; -; . PDBsum 4WRQ; -; . PDBsum 4ZDR; -; . PDBsum 5D2D; -; . PDBsum 5D3F; -; . PDBsum 5EWZ; -; . PDBsum 5EXA; -; . PDBsum 5J31; -; . ProteinModelPortal P63104; -; . SMR P63104; -; . BioGrid 113366; 364; . DIP DIP-563N; -; . IntAct P63104; 570; . MINT MINT-89071; -; . STRING 9606.ENSP00000309503; -; . iPTMnet P63104; -; . PhosphoSitePlus P63104; -; . SwissPalm P63104; -; . BioMuta YWHAZ; -; . DMDM 52000887; -; . DOSAC-COBS-2DPAGE P63104; -; . OGP P63104; -; . UCD-2DPAGE P63104; -; . EPD P63104; -; . MaxQB P63104; -; . PaxDb P63104; -; . PeptideAtlas P63104; -; . PRIDE P63104; -; . TopDownProteomics P63104-1; -. [P63104-1]; . DNASU 7534; -; . Ensembl ENST00000353245; ENSP00000309503; ENSG00000164924. [P63104-1]; . Ensembl ENST00000395951; ENSP00000379281; ENSG00000164924. [P63104-1]; . Ensembl ENST00000395953; ENSP00000379283; ENSG00000164924. [P63104-1]; . Ensembl ENST00000395956; ENSP00000379286; ENSG00000164924. [P63104-1]; . Ensembl ENST00000395957; ENSP00000379287; ENSG00000164924. [P63104-1]; . Ensembl ENST00000395958; ENSP00000379288; ENSG00000164924. [P63104-1]; . Ensembl ENST00000419477; ENSP00000395114; ENSG00000164924. [P63104-1]; . Ensembl ENST00000457309; ENSP00000398599; ENSG00000164924. [P63104-1]; . Ensembl ENST00000522542; ENSP00000430072; ENSG00000164924. [P63104-2]; . GeneID 7534; -; . KEGG hsa:7534; -; . UCSC uc003yjv.3; human. [P63104-1]; . CTD 7534; -; . DisGeNET 7534; -; . GeneCards YWHAZ; -; . HGNC HGNC:12855; YWHAZ; . HPA CAB005065; -; . MIM 601288; gene; . neXtProt NX_P63104; -; . OpenTargets ENSG00000164924; -; . PharmGKB PA37444; -; . eggNOG KOG0841; Eukaryota; . eggNOG COG5040; LUCA; . GeneTree ENSGT00760000119116; -; . HOGENOM HOG000240379; -; . HOVERGEN HBG050423; -; . InParanoid P63104; -; . KO K16197; -; . PhylomeDB P63104; -; . TreeFam TF102003; -; . Reactome R-HSA-111447; Activation of BAD and translocation to mitochondria; . Reactome R-HSA-1445148; Translocation of GLUT4 to the plasma membrane; . Reactome R-HSA-3769402; Deactivation of the beta-catenin transactivating complex; . Reactome R-HSA-392517; Rap1 signalling; . Reactome R-HSA-430116; GP1b-IX-V activation signalling; . Reactome R-HSA-450604; KSRP (KHSRP) binds and destabilizes mRNA; . Reactome R-HSA-512988; Interleukin-3; 5 and GM-CSF signaling; . Reactome R-HSA-5625740; RHO GTPases activate PKNs; . Reactome R-HSA-5628897; TP53 Regulates Metabolic Genes; . Reactome R-HSA-75035; Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex; . SignaLink P63104; -; . SIGNOR P63104; -; . ChiTaRS YWHAZ; human; . EvolutionaryTrace P63104; -; . GeneWiki YWHAZ; -; . GenomeRNAi 7534; -; . PRO PR:P63104; -; . Proteomes UP000005640; Chromosome 8; . Bgee ENSG00000164924; -; . ExpressionAtlas P63104; baseline and differential; . Genevisible P63104; HS; . GO GO:0072562; C:blood microparticle; IDA:UniProtKB; . GO GO:0005737; C:cytoplasm; TAS:ProtInc; . GO GO:0030659; C:cytoplasmic vesicle membrane; TAS:Reactome; . GO GO:0005829; C:cytosol; TAS:Reactome; . GO GO:0070062; C:extracellular exosome; IDA:UniProtKB; . GO GO:0005615; C:extracellular space; IDA:UniProtKB; . GO GO:0005925; C:focal adhesion; IDA:UniProtKB; . GO GO:0042470; C:melanosome; IEA:UniProtKB-SubCell; . GO GO:0005739; C:mitochondrion; IEA:GOC; . GO GO:0005654; C:nucleoplasm; TAS:Reactome; . GO GO:0005634; C:nucleus; IDA:UniProtKB; . GO GO:0045296; F:cadherin binding; IDA:BHF-UCL; . GO GO:0042802; F:identical protein binding; IPI:IntAct; . GO GO:0019901; F:protein kinase binding; IPI:UniProtKB; . GO GO:0003723; F:RNA binding; IDA:UniProtKB; . GO GO:0008134; F:transcription factor binding; IPI:UniProtKB; . GO GO:0031625; F:ubiquitin protein ligase binding; IPI:ParkinsonsUK-UCL; . GO GO:0051683; P:establishment of Golgi localization; IMP:UniProtKB; . GO GO:0090168; P:Golgi reassembly; IMP:UniProtKB; . GO GO:0061024; P:membrane organization; TAS:Reactome; . GO GO:0043066; P:negative regulation of apoptotic process; TAS:ProtInc; . GO GO:0030168; P:platelet activation; TAS:Reactome; . GO GO:1900740; P:positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway; TAS:Reactome; . GO GO:0043488; P:regulation of mRNA stability; TAS:Reactome; . GO GO:0007165; P:signal transduction; TAS:ProtInc; . Gene3D 1.20.190.20; -; 1; . InterPro IPR000308; 14-3-3; . InterPro IPR023409; 14-3-3_CS; . InterPro IPR023410; 14-3-3_domain; . PANTHER PTHR18860; PTHR18860; 1; . Pfam PF00244; 14-3-3; 1; . PIRSF PIRSF000868; 14-3-3; 1; . PRINTS PR00305; 1433ZETA; . SMART SM00101; 14_3_3; 1; . SUPFAM SSF48445; SSF48445; 1; . PROSITE PS00796; 1433_1; 1; . PROSITE PS00797; 1433_2; 1; .

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